Abbott, founded in 1888 and based in Abbott Park, Illinois, is a diversified healthcare company with about 115,000 employees. It operates in medical devices, diagnostics, nutritional products and established pharmaceuticals, and medical devices is its largest segment, spanning continuous glucose monitoring, electrophysiology, structural heart …
10x Genomics, based in Pleasanton, California, is a life science technology company co-founded in 2012. It designs and sells instruments, consumables and software for single-cell and spatial biology, built around Chromium for single-cell analysis, Visium for spatial gene expression and Xenium for in situ …
Accendra Health, formerly Owens & Minor and based in Glen Allen, Virginia, provides products, technology and services that support home-based care through its Apria and Byram Healthcare brands. Following the sale of its legacy Products & Healthcare Services business, it has become a pure-play …
Annovis, based in Malvern, Pennsylvania, is a late-stage clinical biopharmaceutical company developing therapies for neurodegenerative diseases, including Alzheimer's and Parkinson's. Its lead candidate, buntanetap, is an oral small molecule that inhibits the synthesis of several neurotoxic proteins, and it is in Phase 3 development …
Axsome, based in New York, is a commercial-stage biopharmaceutical company founded in 2012 that develops therapies for central nervous system disorders. Its marketed products are Auvelity for major depressive disorder and Alzheimer's disease agitation, Sunosi for excessive daytime sleepiness in narcolepsy and sleep apnea, …
Azenta, formerly Brooks Automation, is a pure-play life sciences tools and services company. It provides sample management solutions, including automated cold storage systems, cryogenic equipment, consumables, informatics, cold-chain logistics and biorepository services, and multiomics services through GENEWIZ, which offers genomic sequencing and gene synthesis. …
Bright Minds, based in New York, is a clinical-stage, pre-revenue biotechnology company developing selective serotonin 5-HT2 receptor agonists for epilepsy and other central nervous system disorders. Its lead candidate, BMB-101, is a 5-HT2C Gq-biased agonist in Phase 2 development for developmental and epileptic encephalopathies …
Compass Pathways develops COMP360, a psilocybin treatment, for treatment-resistant depression. The program has reported two positive Phase 3 trials, and the company has been working toward completing its FDA filing. It has received a Commissioner's National Priority Voucher, which can speed regulatory review, and …
Enlivex, headquartered in Ness Ziona, Israel, is a clinical-stage macrophage reprogramming immunotherapy company founded in 2005. Its lead candidate, Allocetra, is an off-the-shelf allogeneic cell therapy designed to restore macrophages to their homeostatic state. The company is focused on late-stage development in knee osteoarthritis …
Eton Pharmaceuticals, based in Deer Park, Illinois, is a specialty pharmaceutical company incorporated in 2017 that develops, acquires and commercializes treatments for rare diseases. It sells about ten products under its own label through an internal sales force and specialty pharmacy and distributor channels, …