Opaleye Management Inc. filed a Form 4 on August 14, 2026, disclosing a purchase of Sol-Gel Technologies Ltd. ordinary shares on August 12, 2026, and reporting updated beneficial ownership positions across two indirectly held accounts.

Key Highlights

  • Purchase transaction: Opaleye Management Inc. acquired 951 ordinary shares of Sol-Gel Technologies Ltd. at $71.5 per share on August 12, 2026.
  • Security type: The shares are ordinary shares with a par value of NIS 1.00 per share.
  • Post-transaction holding via fund: Following the transaction, 494,887 ordinary shares are beneficially owned indirectly through Opaleye, L.P.
  • Managed account position: An additional 15,000 ordinary shares are held indirectly through a separately managed account.
  • Reporting person's status: Opaleye Management Inc. is identified as a 10% owner of the issuer.
  • Disclaimer of ownership: According to the filing, Opaleye Management Inc. "disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein."

Opaleye Management's August 2026 Purchase and Ownership in Sol-Gel Technologies

According to the filing, Opaleye Management Inc., based in Boston, Massachusetts, reported a purchase of 951 ordinary shares of Sol-Gel Technologies Ltd. (NASDAQ:SLGL) on August 12, 2026, at a price of $71.5 per share. The transaction is coded "P," indicating an open-market purchase. The filing was signed by James Silverman, President, on August 14, 2026.

The filing discloses two indirect beneficial ownership positions. The first, consisting of 494,887 ordinary shares following the reported transaction, is held through Opaleye, L.P., a fund for which Opaleye Management Inc. serves as investment manager. The second position of 15,000 ordinary shares is held through a separately managed account for which Opaleye Management Inc. acts as portfolio manager. No derivative securities were reported in Table II of the filing.

The filing notes that Opaleye Management Inc. disclaims beneficial ownership of the shares except to the extent of its pecuniary interest, and states that the filing "shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose." The form was filed as a single reporting person filing, with no amendment date indicated.

What Was Disclosed

Opaleye Management Inc. disclosed the acquisition of 951 Sol-Gel Technologies ordinary shares at $71.5 each on August 12, 2026, resulting in indirectly held positions of 494,887 shares through its fund and 15,000 shares through a managed account.