FMR LLC and Abigail P. Johnson filed Amendment No. 7 to a Schedule 13G with the SEC on November 4, 2026, disclosing beneficial ownership of common stock in Annexon Inc as of September 30, 2026.

Key Highlights

  • Aggregate beneficial ownership: FMR LLC and Abigail P. Johnson each reported beneficial ownership of 26,288,999.68 shares of Annexon Inc common stock.
  • Percent of class: The reported holdings represent 13.9% of Annexon Inc's outstanding common stock.
  • Sole voting power (FMR LLC): FMR LLC reported sole voting power over 26,285,495 shares, with no shared voting power.
  • Sole dispositive power: Both FMR LLC and Abigail P. Johnson each reported sole dispositive power over 26,288,999.68 shares, with no shared dispositive power.
  • Triggering event date: The date of the event requiring this filing was September 30, 2026.
  • Third-party interests: According to the filing, one or more other persons are known to have the right to receive dividends or proceeds from the sale of the common stock, though no single other person's interest exceeds 5% of total outstanding shares.

FMR LLC and Abigail P. Johnson Disclose Combined Annexon Stake in Amended 13G

FMR LLC, a Delaware-organized holding company located at 245 Summer Street, Boston, Massachusetts, submitted Amendment No. 7 to its Schedule 13G regarding common stock of Annexon Inc (NASDAQ:ANNX), headquartered at 1400 Sierra Point Parkway, Brisbane, California. The filing was signed on November 4, 2026, by Stephanie J. Brown, acting under powers of attorney granted on behalf of both FMR LLC and Abigail P. Johnson.

According to the filing, FMR LLC holds sole voting power over 26,285,495 shares and sole dispositive power over 26,288,999.68 shares. Abigail P. Johnson, identified as an individual reporting person with United States citizenship, reported zero sole or shared voting power, but reported sole dispositive power over the same 26,288,999.68 shares. Both reporting persons disclosed an aggregate beneficial ownership of 26,288,999.68 shares, equating to 13.9% of the class.

The filing states that the securities "were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer." Item 7 of the filing directs readers to Exhibit 99 for identification and classification of the subsidiary through which the securities were acquired. The filing notes that one or more other persons have the right to receive dividends or sale proceeds from the common stock, but specifies that no single other person's interest exceeds 5% of the total outstanding shares.

What Was Disclosed

FMR LLC and Abigail P. Johnson filed Amendment No. 7 to Schedule 13G reporting combined beneficial ownership of 26,288,999.68 shares, or 13.9%, of Annexon Inc common stock, as of September 30, 2026.