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PREA generally requires companies developing new drugs to study their safety and effectiveness in pediatric populations, but it also recognizes that testing unproven therapies in children before adult data are available can raise ethical and safety concerns, particularly for serious, high-mortality conditions like bacteremia. …
Feeding tube placement is a common but clinically important procedure, particularly for hospitalized patients who cannot safely take food or medication orally. Incorrect placement carries real risks, including tubes migrating into the airway rather than the digestive tract, which is why real-time navigation and …
Overall survival is widely considered the gold-standard endpoint in oncology clinical trials, since it directly measures whether a treatment helps patients live longer rather than relying on surrogate markers like tumor response rate or progression-free survival. A nearly nine-month improvement over historical benchmarks, if …
TACTI-004 was designed to evaluate eftilagimod alfa (efti) in combination with pembrolizumab and chemotherapy in a larger, pivotal-stage NSCLC population, building on encouraging earlier-stage data for the drug. The trial's discontinuation followed disappointing results, but the nature of those results — specifically a suppressed …
California Resources Corporation, the Long Beach-based independent oil and gas producer, released preliminary and unaudited summary data on July 14, 2026, covering realized commodity prices and derivative settlements for the three months ended June 30, 2026. The disclosure reveals that the company's realized oil …
Sunda Energy PLC (LSE:SNDA) is an AIM-listed oil and gas exploration and development company focused on building a diversified upstream energy portfolio across the Asia-Pacific region. The company has exploration, appraisal and production interests in Timor-Leste, the Philippines and New Zealand. Its strategy is …
US equities closed higher on Friday ahead of earnings season, with the S&P 500 gaining 0.4%, the Nasdaq 100 rising 0.3% and the Dow adding 150 points. Sentiment was supported by SK Hynix’s strong US market debut, gains in Nvidia, AMD and Meta, and …
SBA Communications Corporation has announced a new offering of senior notes due in 2030, 2031, and 2033, according to a recent filing. The company aims to use the proceeds to repay existing debts, including a 2024 Term Loan and borrowings under its Revolving Credit …
The Trade Desk, Inc. has announced the appointment of Penry Price to its board of directors. Effective July 9, 2026, Price will also serve on the audit committee and as chair of the compensation committee. This strategic move expands the board from six to …
First Hawaiian, Inc. has released its preliminary financial results for the second quarter of 2026, revealing key insights into its performance ahead of the final report. Concurrently, the company has announced a significant merger agreement with TriCo Bancshares, marking a strategic expansion. Investors are …
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