• The move adds to a roughly 177 percent surge earlier in the week tied to melanoma cancer-vaccine data with a partner.
• The FDA grantedFast Track Designationto safusidenib, the company's oral IDH1 inhibitor for IDH1-mutant glioma.
• RPRX shares traded around $61.45 in premarket, up about 1.44 percent from a prior close of $60.58.
● Phase 2 VALIANT data showed verekitug's 400mg twice-yearly dose delivered only a 39% exacerbation reduction versus 56% at the 100mg dose, a setback that first sent shares down about 47% in a single session.
● Sana Biotechnology shares have fallen sharply, most recently closing at $3.74, down 8.78%, on unusually lightVolumewith no freshEarningsor clinical disclosure identified as the trigger.
● First Tracks Biotherapeutics shares have fallen sharply, most recently closing at $41.90, down 7.91%, cooling after a rally driven largely by a single-day jump tied to a competitor's positive CD122 data.
● REGENXBIO shares have fallen sharply, most recently closing at $11.06, down 7.99%, two weeks after reporting Q2 2026 results.
● TransCode Therapeutics shares have fallen, most recently closing at $2.97, down 7.48%, carrying a marketCapitalizationof roughly $3.6 million with only about 1.1 million shares outstanding following a 1-for-28 reverse stock split.
● Regentis Biomaterials shares have fallen, most recently closing at $2.06, down 7.62%, with a marketCapitalizationof roughly $10 million.
● Prime Medicine shares have fallen sharply, most recently closing at $3.24, down 8.47%, amid a broad selloff in speculative biotech as long-term Treasury yields rose to their highest level in nearly two decades.