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Rigel Pharmaceuticals (NASDAQ:RIGL) presented updated data from its ongoing Phase 1b study evaluating R289, an oral prodrug of the dual IRAK1/4 inhibitor R835, in patients with relapsed or refractory (R/R) lower-risk myelodysplastic syndrome. The findings were shared during an oral session at the 67th …
Incyte (NASDAQ:INCY) has announced that the U.S.FDAhas granted Breakthrough Therapy designation to INCA033989, the company’s first-in-class monoclonal antibody designed to target mutant calreticulin (mutCALR). The designation applies to patients with essential thrombocythemia who carry a Type 1 CALR mutation and are resistant or intolerant …
Prime Medicine (NASDAQ:PRME) has unveiled high-impact clinical results for PM359, its investigational autologous hematopoietic stem cell therapy for p47phox chronic granulomatous disease. The data represents the first clinical demonstration of Prime Editing in humans, signaling a potentially transformative step forward for gene-repair technologies.
Sprinklr, Inc. (NYSE:CXM)provides enterprise software for customer-facing functions. Its AI-enabled Unified Customer Experience Management (Unified-CXM) platform supports service, marketing, and other front-office teams by connecting workflows across departments, enabling engagement across digital channels, and using AI insights to manage customer interactions.
Market Movers (Yesterday):Capricor Therapeutics, Inc. surged 371.07%, leading the gainers, followed by iRobot Corporation which jumped 73.85%. Acrivon Therapeutics and several other small-cap biotech names also rallied sharply on short covering and FDA-driven optimism. On the downside, WORK Medical Technology Group Ltd fell 35.94%, …
Franklin Resources, Inc. (NYSE:BEN) is currently covered by TD Cowen with a Buy recommendation. Analyst Bill Katz initiated coverage on December 3, 2025. TD Cowen has assigned a price target of USD 31.00.
UiPath (NYSE:PATH) is a global automation leader, enabling enterprises to leverage AI agents for autonomous execution and optimization of complex business processes. The UiPath Platform™ integrates controlled agency, developer flexibility, and seamless system integration to help organizations scale agentic automation safely and efficiently.
Ascentage Pharma Group International (NASDAQ:AAPG) announced that regulators in both the United States and Europe have cleared its global registrational Phase III clinical trial of olverembatinib for the first-line treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). The study, known as POLARIS-1 (NCT06051409), …
Protara Therapeutics, Inc. (NASDAQ:TARA), a clinical-stage company focused on therapies for cancer and rare diseases, announced the pricing of its underwritten public offering of common stock. The offering comprises 13,043,479 shares, which were priced at USD 5.75 per share. All shares included in the …
Market Movers:On Wednesday, the top gainers were Capricor Therapeutics, Inc.(+371.07%), followed by iRobot Corporation (+73.85%). On the WORK Medical Technology Group LTD (-35.94%), and Agroz Inc. (-33.61%) declined the most the same day.
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