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Prothena Corporation plc

Company price
8.47 USD -0.41 ( 4.62%)
Last update at 2026-10-30T20:00:00Z
VOLUME
449717
Market Cap
1072.75M

Momentum Score

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Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation in the United States. The company is involved in developing birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, for the treatment of Parkinson's disease and other related synucleinopathies which is in Phase IIb clinical trial; NNC6019 that is in Phase lI clinical trial for the treatment of ATTR amyloidosis; and BMS-986446 and PRX012, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX123, a dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease; and PRX019 for the treatment of neurogenerative diseases, as well as TDP-43 for the treatment of amyotrophic lateral sclerosis. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and a collaboration agreement with Bristol-Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. The company was incorporated in 2012 and is based in Dublin, Ireland.

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Day Price Range
8.35
Low
8.90
High
52 Week Price Range
19.65
Low
77.13
High

Momentum Score

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A unique technical analysis driven score developed by Kalkine showing momentum in stock prices based on select technical indicators identified.

Score - Rating
>= 1 - Low / > 1 but < 2 - Below Average / > 2 but < 3 - Average / > 3 but < 4 - Above Average / > 4 - High

Key Metrics*

Previous Close
8.88
Dividend Yield
-
Revenue TTM
89.25M
Revenue Per Share
1.67
Gross Profit TTM
-81.66M
Debt / Equity
0.02
ROE
-31.07%
Net Debt
-608.35M
ROCE
-29.87%
Diluted EPS TTM
-3.21

Insight Announcement

Key Financials*

Income Statement

Balance Sheet

Change in Cash

Total Operating Cash

Dividends Paid

Breakdown 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Type yearly yearly yearly yearly yearly
Date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Income before tax -160.48M -125.61M 71.92M -111.43M -77.30M
Net income -147.03M -116.95M 66.97M -111.14M -77.68M
Selling general administrative 61.84M 49.90M 46.32M 38.70M 35.74M
Gross profit 82.96M 53.91M 200.58M 0.85M -50.02M
Reconciled depreciation 0.93M 0.74M 6.80M 6.98M 6.82M
Ebit -191.04M -131.56M 71.97M -112.73M -85.70M
Ebitda -190.11M -130.81M 78.78M -105.76M -85.82M
Depreciation and amortization 0.93M 0.74M 6.80M 6.98M -0.12M
Non operating income net other - - -0.10M -0.06M 0.20M
Operating income -191.04M -131.56M 71.97M -112.73M -85.70M
Other operating expenses 282.41M 185.46M 128.60M 113.59M 86.57M
Interest expense - 6.70M 6.75M 8.28M 8.20M
Tax provision -13.45M -8.66M 4.95M -0.28M 0.38M
Interest income 31.01M 6.35M 0.04M 1.37M 8.20M
Net interest income 31.01M 6.35M 0.04M 1.37M 8.20M
Non recurring - - - - -0.06M
Income tax expense -13.45M -8.66M 4.95M -0.28M 0.38M
Total revenue 91.37M 53.91M 200.58M 0.85M 0.81M
Total operating expenses 282.41M 185.46M 128.60M 113.59M 86.57M
Cost of revenue 8.41M 6.74M 82.28M 74.88M 50.84M
Total other income expense net 30.56M 5.95M -0.05M 1.31M 8.40M
Net income from continuing ops -147.03M -116.95M 66.97M -111.14M -77.68M
Net income applicable to common shares - -116.95M 66.97M -111.14M -77.68M
Breakdown 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Type yearly yearly yearly yearly yearly
Date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Total assets 696.38M 758.03M 609.37M 332.98M 419.27M
Other current assets 19.10M 8.69M 5.71M 2.54M 2.65M
Total liab 135.02M 135.99M 143.32M 148.97M 146.35M
Total stockholder equity 561.37M 622.04M 466.04M 184.01M 272.92M
Deferred long term liab - - 102.93M 110.24M 110.24M
Other current liab -37.02M 22.96M 16.16M 11.29M 6.79M
Common stock 0.54M 0.52M 0.47M 0.40M 0.40M
Capital stock 0.54M 0.52M 0.47M 0.40M 0.40M
Retained earnings -980.03M -833.00M -716.05M -783.03M -671.88M
Other liab - 85.85M 103.49M 110.80M 110.80M
Other assets - 30.93M 10.42M 31.14M 13.74M
Cash 620.18M 710.41M 579.09M 295.38M 375.72M
Total current liabilities 56.89M 50.15M 33.45M 25.85M 17.71M
Current deferred revenue 67.41M 11.44M 7.66M 4.93M 4.58M
Net debt -608.35M -703.93M -566.77M -277.54M -352.78M
Short term debt 1.11M 6.47M 5.94M 5.51M 5.10M
Short long term debt total 11.84M 6.47M 12.33M 17.84M 22.94M
Other stockholder equity 1540.86M 1454.52M 1181.63M 966.64M 944.41M
Property plant equipment - 8.01M 2.01M 2.55M 3.87M
Total current assets 639.28M 719.10M 584.81M 299.28M 378.38M
Net tangible assets - 622.04M 466.04M 184.01M 272.92M
Net receivables 5.16M 0.06M 0.01M 0.01M 0.07M
Inventory -5.16M -0.06M - 1.35M -0.07M
Accounts payable 25.39M 9.27M 3.69M 4.12M 1.24M
Accumulated other comprehensive income - - - - -8.01M
Common stock total equity - - 0.47M 0.40M 0.40M
Retained earnings total equity - - -716.05M -783.03M -671.88M
Non currrent assets other 40.24M 12.72M 3.35M 1.69M 3.79M
Deferred long term asset charges - - - - 9.96M
Non current assets total 57.10M 38.94M 24.56M 33.69M 40.89M
Capital lease obligations 11.84M 6.47M 12.33M 17.84M 22.94M
Breakdown 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Type yearly yearly yearly yearly yearly
Date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Investments -1.41M -0.46M -0.57M -0.20M -0.55M
Change to liabilities - -1.99M -0.14M 7.73M -0.54M
Total cashflows from investing activities - -0.46M -0.57M -0.20M -0.55M
Total cash from financing activities 45.10M 241.46M 190.33M 0.21M 0.23M
Change to operating activities - -16.81M -10.28M -4.30M -4.37M
Net income -147.03M -116.95M 66.97M -111.14M -77.68M
Change in cash -90.22M 132.17M 282.36M -80.34M -53.29M
Begin period cash flow 710.41M 580.45M 298.08M 378.43M 431.71M
End period cash flow 620.18M 712.62M 580.45M 298.08M 378.43M
Total cash from operating activities -133.91M -108.82M 92.61M -80.36M -52.97M
Issuance of capital stock 232.78M 223.62M 174.79M 78.37M -
Depreciation 0.93M 0.74M 6.80M 6.98M 6.82M
Other cashflows from investing activities - - - - 0.01M
Change to inventory -8.90M - -10.28M - -
Change to account receivables -5.16M 0.08M 0.01M 0.05M 0.05M
Sale purchase of stock - - 93.59M 0.21M 0.23M
Other cashflows from financing activities 45.10M 17.84M 190.33M 0.21M 0.23M
Change to netincome - 20.19M 4.57M -1.69M -1.25M
Capital expenditures 2.81M 0.46M 0.57M 0.20M 0.56M
Change receivables - - 0.01M 0.05M -
Cash flows other operating - - 20.07M 23.18M 24.93M
Cash and cash equivalents changes - - 282.36M -80.34M -53.29M
Change in working capital -20.53M -18.80M -10.40M 3.48M -4.45M
Stock based compensation 40.91M 31.32M 24.66M 22.01M 23.59M
Other non cash items 7.50M 6.00M 38.74M 28.19M 51.35M
Free cash flow -136.72M -109.28M 92.03M -80.56M -53.52M

Peer Comparison*

Sector: Healthcare Industry: Biotechnology

Stock Name
Change
(USD)
Price
(USD)
Trailing
PE (x)
Forward
PE (x)
Price Sales
TTM (x)
Price to Book Value (x)
Enterprise Value
to Revenue (x)
Enterprise Value
to EBITDA (x)
PRTA
Prothena Corporation plc
-0.41
4.62%
8.47 - 64.10 13.08 2.13 6.43 -3.09
NVO
Novo Nordisk A/S
0.86
2.20%
40.00 41.58 31.15 2.13 32.99 2.11 4.70
VRTX
Vertex Pharmaceuticals Inc
18.88
3.50%
558.88 30.22 24.27 10.36 6.50 9.99 24.66
REGN
Regeneron Pharmaceuticals Inc
109.12
13.33%
927.89 29.07 20.12 7.57 3.82 6.95 19.42
ARGNF
argenx SE
-
-%
900.30 45.77 31.25 13.84 7.12 11.38 36.06

Profile*

Prothena Corporation plc

Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation in the United States. The company is involved in developing birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, for the treatment of Parkinson's disease and other related synucleinopathies which is in Phase IIb clinical trial; NNC6019 that is in Phase lI clinical trial for the treatment of ATTR amyloidosis; and BMS-986446 and PRX012, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX123, a dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease; and PRX019 for the treatment of neurogenerative diseases, as well as TDP-43 for the treatment of amyotrophic lateral sclerosis. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and a collaboration agreement with Bristol-Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. The company was incorporated in 2012 and is based in Dublin, Ireland.

77 Sir John Rogerson?s Quay, Dublin, Ireland, D02 VK60

353 1 236 2500

173

Name Title Year Born
Dr. Gene G. Kinney Ph.D. Pres, CEO & Director 1969
Mr. Tran B. Nguyen M.B.A. CFO & Chief Strategy Officer 1974
Mr. Brandon S. Smith Chief Operating Officer 1975
Ms. Carol D. Karp Chief Regulatory Officer 1953
Dr. Hideki Garren M.D., Ph.D. Chief Medical Officer 1965
Ms. Karin L. Walker CPA, CPA Chief Accounting Officer & Controller 1963
Dr. Wagner M. Zago Chief Scientific Officer 1973
Ms. Jennifer Zibuda Director of Investor Relations & Communication NA
Mr. Michael J. Malecek Chief Legal Officer 1966
Ms. Yvonne M. Tchrakian Company Sec. NA

Disclaimer - (*)This information, including any data, is sourced from Unicorn Data Services SAS, trading as EOD Historical Data (“EODHD”) on an ‘as is’ basis, using their API. We cannot guarantee the completeness or validity of the information and data provided on this page, as well as via the API. In some cases, the data may include analyst ratings or recommendations sourced through the EODHD API, which are intended solely for general information purposes.
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