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MeiraGTx Holdings PLC

Company price
9.63 USD 0.11 ( 1.16%)
Last update at 2026-11-04T18:27:00Z
VOLUME
218612
Market Cap
1225.51M
P/E
14.67

Momentum Score

…

MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.

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Day Price Range
9.39
Low
9.92
High
52 Week Price Range
6.62
Low
15.35
High

Momentum Score

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Score - Rating
>= 1 - Low / > 1 but < 2 - Below Average / > 2 but < 3 - Average / > 3 but < 4 - Above Average / > 4 - High

Key Metrics*

Previous Close
9.52
Dividend Yield
-
Revenue TTM
397.50M
Revenue Per Share
4.75
Gross Profit TTM
389.35M
Debt / Equity
-15.31
ROE
72.17%
Net Debt
22.75M
ROCE
-83.70%
Diluted EPS TTM
0.87

Key Financials*

Income Statement

Balance Sheet

Change in Cash

Total Operating Cash

Dividends Paid

Breakdown 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Type yearly yearly yearly yearly yearly
Date 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Income before tax -114.20M -147.79M -84.03M -129.62M -79.56M
Net income -114.20M -147.79M -84.03M -142.88M -71.98M
Selling general administrative 52.90M 54.22M 47.29M 46.55M 43.77M
Selling and marketing expenses - - 13.43M - -
Gross profit 76.55M 9.49M 14.02M 15.92M 37.70M
Reconciled depreciation 12.61M 12.68M 12.31M 8.72M 7.87M
Ebit -102.00M -134.52M -70.78M -116.36M -73.19M
Ebitda -89.40M -121.69M -57.05M -115.58M -72.98M
Depreciation and amortization 12.61M 12.83M 13.73M 0.78M 0.21M
Non operating income net other - - - -8.68M -6.08M
Operating income -105.97M -164.21M -137.06M -116.36M -73.19M
Other operating expenses 187.36M 197.49M 151.08M 132.28M 110.89M
Interest expense 12.20M 13.27M 13.24M 4.95M 0.29M
Interest income 1.82M 4.14M 2.15M 0.78M 0.21M
Net interest income -10.38M -9.13M -10.54M -4.17M -0.08M
Income tax expense - - 13.56M 13.26M -7.58M
Total revenue 81.39M 33.28M 14.02M 15.92M 37.70M
Total operating expenses 182.52M 173.70M 151.08M 132.28M 110.89M
Cost of revenue 4.84M 23.79M 13.73M - -
Total other income expense net -8.23M 16.42M 53.03M -13.26M -6.37M
Net income from continuing ops -114.20M -147.79M -131.56M -129.98M -79.56M
Net income applicable to common shares - - - -129.62M -79.56M
Breakdown 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Type yearly yearly yearly yearly yearly
Date 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Total assets 244.43M 269.75M 458.17M 318.24M 320.16M
Intangible assets 0.58M 0.82M 1.12M 2.08M 2.57M
Other current assets 7.54M 8.85M 6.64M 1.67M 2.42M
Total liab 250.22M 201.92M 319.99M 200.50M 134.76M
Total stockholder equity -5.79M 67.83M 138.18M 117.74M 185.40M
Deferred long term liab - - - 0.19M 0.78M
Other current liab 83.18M 28.32M 43.92M 46.45M 27.59M
Common stock 0.00M 0.00M 0.00M 0.00M 0.00M
Capital stock 0.00M 0.00M 0.00M 0.00M 0.00M
Retained earnings -816.22M -702.02M -554.23M -470.20M -340.59M
Other liab - - - 30.06M 46.28M
Other assets - - - 2.14M 2.19M
Cash 65.93M 103.66M 129.57M 115.52M 137.70M
Total current liabilities 122.56M 60.78M 67.08M 82.07M 68.13M
Current deferred revenue 1.78M 4.83M 2.93M 15.12M 21.82M
Net debt 22.75M -18.86M -40.30M -23.27M -113.97M
Short term debt 27.54M 4.05M 4.19M 3.88M 3.37M
Short long term debt 24.65M - - - -
Short long term debt total 88.69M 84.80M 89.26M 92.25M 23.73M
Other stockholder equity 808.02M 773.57M 693.84M 581.89M 528.66M
Property plant equipment - - - 109.27M 126.29M
Total current assets 91.76M 123.52M 159.62M 154.34M 183.24M
Long term investments 6.75M 6.75M 6.77M 6.33M 6.66M
Net tangible assets - - - 116.40M 183.61M
Net receivables 18.29M 10.63M 23.41M 29.02M 35.02M
Long term debt 49.69M 73.22M 72.12M 71.30M 0.95M
Inventory 0.00M 0.39M - 8.13M 8.10M
Accounts payable 10.07M 23.59M 16.04M 16.62M 15.35M
Accumulated other comprehensive income 2.41M -3.72M -1.44M 6.05M -2.67M
Common stock total equity - - - 0.00M 0.00M
Retained earnings total equity - - - -470.20M -340.59M
Non currrent assets other 3.41M 3.01M 1.92M 1.22M 1.21M
Non current assets total 152.67M 146.23M 298.55M 163.90M 136.92M
Capital lease obligations 14.35M 11.58M 17.14M 21.21M 23.73M
Long term debt total - - - 71.30M 0.95M
Breakdown 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Type yearly yearly yearly yearly yearly
Date 2025-12-31 2024-12-31 2023-12-31 2022-12-31 2021-12-31
Investments - 23.48M -25.64M -44.96M -6.50M
Change to liabilities - - - 4.43M 13.96M
Total cashflows from investing activities -4.11M 23.48M 34.03M -44.96M -61.72M
Net borrowings -0.03M 0.00M 0.00M 75.00M -0.00M
Total cash from financing activities 12.27M 54.53M 84.02M 95.20M 1.71M
Change to operating activities - - - 16.63M 8.72M
Net income -114.20M -147.79M -84.03M -129.62M -79.56M
Change in cash -37.48M -24.98M 15.13M -22.19M -71.82M
Begin period cash flow 105.67M 130.65M 115.52M 137.70M 209.52M
End period cash flow 68.19M 105.67M 130.65M 115.52M 137.70M
Total cash from operating activities -46.36M -104.50M -105.36M -73.10M -10.53M
Issuance of capital stock 15.07M 59.39M 86.95M 25.00M 0.00M
Depreciation 12.70M 12.68M 13.72M 8.72M 7.87M
Other cashflows from investing activities -0.28M 28.43M 54.21M - -8.87M
Dividends paid - - 0.00M 0.00M -
Change to inventory 0.43M -0.39M 0.00M - 9.03M
Change to account receivables -7.27M 9.43M 4.83M 1.03M 16.39M
Sale purchase of stock - - -1.52M 0.23M 1.71M
Other cashflows from financing activities -3.03M -4.86M -7.93M 70.20M 1.71M
Change to netincome - - - 28.62M 27.14M
Capital expenditures 3.83M 4.96M 20.17M 44.96M 55.22M
Change receivables - - - - 16.39M
Cash flows other operating - - - 14.74M 3.67M
Cash and cash equivalents changes - - - -22.86M -70.54M
Change in working capital 28.03M 29.64M -0.98M 9.62M 31.28M
Stock based compensation 22.11M 25.19M 27.72M 28.62M 20.78M
Other non cash items 5.01M -24.22M -61.80M 9.55M 2.74M
Free cash flow -50.19M -109.45M -125.54M -118.06M -65.75M

Peer Comparison*

Sector: Healthcare Industry: Biotechnology

Stock Name
Change
(USD)
Price
(USD)
Trailing
PE (x)
Forward
PE (x)
Price Sales
TTM (x)
Price to Book Value (x)
Enterprise Value
to Revenue (x)
Enterprise Value
to EBITDA (x)
MGTX
MeiraGTx Holdings PLC
0.11
1.16%
9.63 14.67 64.10 3.08 5.74 3.04 11.40
NVO
Novo Nordisk A/S
2.50
6.21%
42.69 41.58 31.15 2.13 32.99 2.11 4.70
VRTX
Vertex Pharmaceuticals Inc
18.19
3.43%
548.95 30.22 24.27 10.36 6.50 9.99 24.66
REGN
Regeneron Pharmaceuticals Inc
-29.09
2.99%
944.27 29.07 20.12 7.57 3.82 6.95 19.42
ARGNF
argenx SE
-
-%
900.30 45.77 31.25 13.84 7.12 11.38 36.06

Profile*

MeiraGTx Holdings PLC

MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GAD in Phase 2 trial for Parkinson's disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase ½ clinical trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company's products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer's disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson's disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.

655 Third Avenue, New York, NY, United States, 10017

646 860 7985

393

Name Title Year Born
Dr. Alexandria Forbes CEO, Pres & Director 1965
Mr. Richard Brian Giroux B.A. COO & CFO 1973
Dr. Robert K. Zeldin M.D. Chief Medical Officer 1963
Mr. Robert J. Wollin J.D. Gen. Counsel & Sec. 1977
Dr. Stuart Naylor Ph.D. Chief Devel. Officer 1963
Dr. Michel Michaelides M.D. Head of Clinical Ophthalmology NA
Ms. Christine Elise Sheehy Sr. VP of Global Integration 1967
Mr. Joel P. Brooks Sr. VP of Fin. 1959
Mr. Tim Randall Sr. VP of Risk & Internal Controls NA
Dr. Alastair Leighton Ph.D. Sr. VP of Manufacturing & Supply Chain NA

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