Opaleye Management Inc. filed a Form 4 on October 26, 2026, disclosing purchases of common stock of Alpha Cognition Inc. (NASDAQ:ACOG) on October 22 and October 23, 2026.

Key Highlights

  • October 22 purchase: Opaleye Management Inc. acquired 17,117 shares of Alpha Cognition common stock at a weighted average price of $8.3266, with individual transactions ranging from $8.31 to $8.40.
  • October 23 purchase: An additional 14,973 shares were acquired at a weighted average price of $8.2344, with individual transactions ranging from $8.02 to $8.34.
  • Post-transaction holdings via the Fund: Following the October 23 purchase, Opaleye, L.P. held 3,291,984 shares of common stock indirectly through Opaleye Management Inc.
  • Managed Account holdings: An additional 100,000 shares are held indirectly through a separately managed account for which Opaleye Management Inc. serves as portfolio manager.
  • Reporting relationship: Opaleye Management Inc. is identified as a 10% owner of Alpha Cognition Inc.

Opaleye Management Adds to Alpha Cognition Position Across Two Trading Sessions

According to the filing, Opaleye Management Inc., headquartered at One Boston Place, 26th Floor, Boston, Massachusetts 02108, reported two open-market purchase transactions in the common stock of Alpha Cognition Inc. Both transactions were made on behalf of Opaleye, L.P., a fund for which Opaleye Management Inc. serves as investment manager. The filing was signed by James Silverman, President of Opaleye Management Inc.

On October 22, 2026, the firm acquired 17,117 shares at a weighted average price of $8.3266 per share, with individual transaction prices ranging from $8.31 to $8.40. The following day, October 23, 2026, an additional 14,973 shares were acquired at a weighted average price of $8.2344 per share, with individual prices ranging from $8.02 to $8.34. Both prices are described in the filing as weighted averages across multiple transactions. The filing notes that full per-price detail is available upon request from the SEC staff, the issuer, or a security holder.

Following these two transactions, the filing reports that 3,291,984 shares are held indirectly by Opaleye Management Inc. through Opaleye, L.P. A separate line in the filing also discloses 100,000 shares held indirectly through a managed account. The filing includes a standard disclaimer stating that Opaleye Management Inc. "disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein," and that the filing "shall not be construed as an admission" of beneficial ownership for Section 16(a) or any other purpose.

What Was Disclosed

Opaleye Management Inc. disclosed two purchases totaling 32,090 shares of Alpha Cognition Inc. common stock on October 22 and 23, 2026, at weighted average prices of $8.3266 and $8.2344, respectively, bringing indirect holdings through Opaleye, L.P. to 3,291,984 shares.