Joshua J. Ofman, Chief Executive Officer and Director of GRAIL, Inc. (NASDAQ:GRAL), filed a Form 4 on September 23, 2026, reporting stock option exercises and multiple common stock sales that took place on September 21, 2026, all conducted under a pre-established Rule 10b5-1 trading plan.

Key Highlights

  • Option exercise: Ofman exercised a stock option for 26,452 shares of common stock at an exercise price of $14 per share on September 21, 2026.
  • Total shares sold: Ofman disposed of a combined 61,452 shares of common stock across eight separate sale transactions on September 21, 2026.
  • Sale price range: Individual sale transaction weighted average prices ranged from $92.3152 to $110 per share, with actual per-share prices spanning as low as $92.04 and as high as $100.69 across the multi-price tranches, plus a fixed-price sale of 10,000 shares at $110.
  • Remaining ownership: Following all reported transactions, Ofman directly beneficially owned 362,271 shares of common stock.
  • Trading plan: According to the filing, the sale transactions were made pursuant to a Rule 10b5-1 trading plan adopted on December 2, 2025.
  • Option details: The exercised option was originally granted on March 6, 2020, with a performance condition determined to be met on November 1, 2024; as of September 21, 2026, approximately 61% of the option shares had vested, and approximately 39% remained unvested.
  • Remaining options: After the exercise, Ofman held 37,032 stock options directly with an exercise price of $14 and an expiration date of March 5, 2030.

GRAIL CEO Reports Option Exercise and Rule 10b5-1 Plan Sales on September 21, 2026

According to the Form 4 filed with the SEC, Joshua J. Ofman, who serves as both Chief Executive Officer and Director of GRAIL, Inc., exercised a stock option covering 26,452 shares of common stock at a price of $14 per share on September 21, 2026, using transaction code "M." The option was originally granted on March 6, 2020, and its performance condition was determined to be met on November 1, 2024. The filing states that the option vests in thirty-six substantially equal monthly installments beginning December 1, 2024, with approximately 61% vested as of the transaction date.

On the same date, Ofman disposed of shares across eight separate sale transactions, totaling 61,452 shares. Several of the reported prices are weighted averages across multiple intra-day transactions. Specifically, 2,125 shares were sold at a weighted average of $92.3152 (range: $92.04 to $92.93), 1,454 shares at $93.606 (range: $93.04 to $93.90), 37,752 shares at $94.9828 (range: $94.50 to $95.00), 6,200 shares at $96.4308 (range: $96.00 to $96.71), 1,400 shares at $97.8414 (range: $97.74 to $98.00), 421 shares at $99.8499 (range: $99.42 to $100.28), 2,100 shares at $100.6805 (range: $100.68 to $100.69), and 10,000 shares at a fixed price of $110.

The filing notes that all sale transactions were executed pursuant to a Rule 10b5-1 trading plan adopted on December 2, 2025. Following all reported transactions, Ofman directly beneficially owned 362,271 shares of common stock and retained 37,032 stock options with a $14 exercise price expiring March 5, 2030. The Form 4 was signed by Abram Barth as Attorney-in-Fact for Joshua Ofman on September 23, 2026.

What Was Disclosed

The filing reports a stock option exercise of 26,452 shares at $14 and the sale of 61,452 total shares of GRAIL, Inc. common stock by CEO Joshua J. Ofman on September 21, 2026, all conducted under a Rule 10b5-1 plan adopted December 2, 2025, leaving him with 362,271 shares directly owned.