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Last update at 2024-07-25T16:20:00Z
Life Sciences Virtual Investor Forum: Presentations Now Available for Online Viewing
Fri 10 Mar 23, 01:35 PMLife Sciences Virtual Investor Forum Agenda Announced for March 9th
Tue 07 Mar 23, 01:35 PM| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -66.14700M | -60.56100M | -59.17300M | -51.37300M | -48.43500M |
| Minority interest | - | - | - | - | - |
| Net income | -64.87500M | -58.11800M | -56.53700M | -48.67100M | -48.43500M |
| Selling general administrative | 16.55M | 15.39M | 13.54M | 14.73M | 15.72M |
| Selling and marketing expenses | - | - | - | - | - |
| Gross profit | 1.18M | 1.75M | 0.55M | 2.22M | 2.52M |
| Reconciled depreciation | 2.52M | 2.44M | 2.64M | 2.70M | 2.42M |
| Ebit | -67.41900M | -63.20800M | -63.10200M | -57.11100M | -53.65100M |
| Ebitda | -63.62500M | -60.76500M | -60.46600M | -54.40900M | -51.23000M |
| Depreciation and amortization | 3.79M | 2.44M | 2.64M | 2.70M | 2.42M |
| Non operating income net other | - | 0.21M | 1.30M | 3.06M | 2.84M |
| Operating income | -67.41900M | -60.76500M | -60.46600M | -54.40900M | -51.23000M |
| Other operating expenses | 68.60M | 62.52M | 61.01M | 56.63M | 53.75M |
| Interest expense | 0.00200M | 0.00200M | 0.00600M | 0.02M | 0.04M |
| Tax provision | - | - | - | - | - |
| Interest income | 1.27M | 0.21M | 1.30M | 3.06M | 2.84M |
| Net interest income | 1.26M | 0.21M | 1.30M | 3.04M | 2.80M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | -1.27200M | -2.44300M | -2.63600M | -2.70200M | 2.84M |
| Total revenue | 1.18M | 1.75M | 0.55M | 2.22M | 2.52M |
| Total operating expenses | 68.60M | 62.52M | 61.01M | 56.63M | 53.75M |
| Cost of revenue | - | - | - | - | 0.00000M |
| Total other income expense net | 1.27M | 0.20M | 1.29M | 3.04M | 2.79M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | -66.14700M | -60.56100M | -59.17300M | -51.37300M | -48.43500M |
| Net income applicable to common shares | -66.14700M | -60.56100M | -59.17300M | -51.37300M | -48.43500M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 75.55M | 110.86M | 174.74M | 143.84M | 188.57M |
| Intangible assets | - | - | - | 9.59M | 16.38M |
| Earning assets | - | - | - | - | - |
| Other current assets | 0.15M | 0.17M | 0.31M | 0.25M | 0.65M |
| Total liab | 32.90M | 28.25M | 27.47M | 28.70M | 31.67M |
| Total stockholder equity | 42.66M | 82.61M | 147.27M | 115.14M | 156.91M |
| Deferred long term liab | - | - | 9.31M | 9.59M | 16.38M |
| Other current liab | 11.16M | 5.29M | 4.40M | 3.77M | 3.95M |
| Common stock | 0.01000M | 0.07M | 0.07M | 0.04M | 0.03M |
| Capital stock | 0.01000M | 0.07M | 0.07M | 0.04M | 0.03M |
| Retained earnings | -414.30100M | -357.01900M | -290.87200M | -230.31100M | -171.13800M |
| Other liab | - | - | - | 0.13M | - |
| Good will | - | - | - | - | - |
| Other assets | - | 9.40M | 10.41M | 10.69M | 17.54M |
| Cash | 23.96M | 15.86M | 16.44M | 32.51M | 26.18M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 20.40M | 12.12M | 10.08M | 8.30M | 8.86M |
| Current deferred revenue | 3.00M | 0.88M | 0.53M | - | 0.54M |
| Net debt | -6.68500M | 4.44M | 4.16M | -9.70100M | -1.17000M |
| Short term debt | 4.78M | 4.17M | 3.20M | 2.53M | 2.21M |
| Short long term debt | - | - | - | - | - |
| Short long term debt total | 17.27M | 20.30M | 20.59M | 22.81M | 25.01M |
| Other stockholder equity | 456.94M | 439.72M | 438.11M | 345.39M | 327.90M |
| Property plant equipment | - | 21.68M | 9.09M | 26.30M | 30.28M |
| Total current assets | 49.91M | 79.78M | 136.63M | 100.44M | 127.07M |
| Long term investments | - | 0.00000M | 8.04M | 0.00000M | 7.50M |
| Net tangible assets | - | 82.61M | 147.27M | 115.14M | 156.91M |
| Short term investments | 23.79M | 61.77M | 112.15M | 67.94M | 93.39M |
| Net receivables | - | - | - | - | - |
| Long term debt | - | - | - | - | - |
| Inventory | - | - | - | - | - |
| Accounts payable | 1.46M | 1.78M | 1.94M | 2.00M | 2.17M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | 0.00600M | -0.16100M | -0.04500M | 0.01M | 0.11M |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | - | 0.07M | 0.04M | 0.03M |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | - | -290.87200M | -230.31100M | -171.13800M |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 6.84M | 9.40M | 20.98M | 23.03M | 48.48M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 25.64M | 31.08M | 38.11M | 43.40M | 61.50M |
| Capital lease obligations | 17.27M | 20.30M | 20.59M | 22.81M | 25.01M |
| Long term debt total | - | - | - | - | 0.00200M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 58.35M | -52.57400M | 32.48M | 12.05M | -81.54700M |
| Change to liabilities | 0.70M | 0.41M | -0.89300M | -0.93500M | -0.25700M |
| Total cashflows from investing activities | 58.35M | -53.25300M | 32.48M | 10.80M | -87.20100M |
| Net borrowings | -0.01300M | 0.04M | -0.20800M | -0.26600M | -0.42700M |
| Total cash from financing activities | -2.04000M | 89.38M | 13.39M | 79.60M | 82.48M |
| Change to operating activities | -0.32500M | -0.86900M | 12.26M | -30.36000M | 1.40M |
| Net income | -66.14700M | -60.56100M | -59.17300M | -51.37300M | -48.43500M |
| Change in cash | -0.57700M | -16.06900M | 6.32M | 14.93M | -47.18800M |
| Begin period cash flow | 17.54M | 33.60M | 27.28M | 12.35M | 59.54M |
| End period cash flow | 16.96M | 17.54M | 33.60M | 27.28M | 12.35M |
| Total cash from operating activities | -56.88800M | -52.19800M | -39.55300M | -75.46800M | -42.47000M |
| Issuance of capital stock | 0.29M | 89.09M | 13.54M | 57.00M | 82.67M |
| Depreciation | 2.52M | 2.44M | 2.64M | 2.70M | 2.42M |
| Other cashflows from investing activities | - | - | - | 12.05M | -81.54700M |
| Dividends paid | - | - | - | - | - |
| Change to inventory | - | - | - | - | - |
| Change to account receivables | - | - | - | - | - |
| Sale purchase of stock | -2.51800M | 81.04M | 13.54M | 79.87M | 82.91M |
| Other cashflows from financing activities | 0.20M | 0.30M | 0.06M | 22.87M | 0.24M |
| Change to netincome | - | 3.36M | 5.62M | 4.13M | 4.33M |
| Capital expenditures | 0.73M | 0.68M | 0.40M | 1.25M | 5.65M |
| Change receivables | - | - | - | - | - |
| Cash flows other operating | - | 1.89M | 13.32M | -28.71400M | 0.88M |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | - | -16.06900M | 6.32M | 14.93M | -47.18800M |
| Change in working capital | 0.72M | 0.20M | 11.36M | -31.01900M | 0.62M |
| Stock based compensation | 3.64M | 3.36M | 3.91M | 4.13M | 4.32M |
| Other non cash items | 2.38M | 2.10M | 1.74M | 1.37M | -1.39300M |
| Free cash flow | -57.61600M | -52.87700M | -39.94800M | -76.71900M | -48.12400M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to Revenue (x) | Enterprise Value to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| SYBX Synlogic Inc |
0.01 0.58% | 1.72 | - | - | 5.92 | 1.41 | 0.28 | 0.18 |
| NVO Novo Nordisk A/S |
-2.29 1.74% | 129.31 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
3.80 2.90% | 135.00 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
3.67 0.75% | 494.48 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
22.92 2.16% | 1083.78 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotics to treat metabolic diseases in the United States. Its pipeline include SYNB1618, an orally administered, non-systemically absorbed drug candidate to treat phenylketonuria; SYNB1934, an orally administered, non-systemically absorbed drug candidate, which is in Phase III clinical trial to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate, which is in Phase I clinical to treat homocystinuria; SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase II clinical trial for the treatment of enteric hyperoxaluria; and SYNB2081 to lower uric acid for the potential treatment of gout. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc. for the research and pre-clinical development of a synthetic biotic medicine for the treatment of inflammatory bowel disease; and Ginkgo Bioworks, Inc. Synlogic, Inc. is based in Cambridge, Massachusetts.
301 Binney Street, Cambridge, MA, United States, 02142
| Name | Title | Year Born |
|---|---|---|
| Dr. Aoife M. Brennan BAO, BCh, M.D., MB, MMSc | Pres, CEO & Director | 1976 |
| Mr. Antoine Awad | Chief Operating Officer | 1980 |
| Dr. Timothy K. Lu M.D., Ph.D. | Co-Founder & Member of Scientific Advisory Board | 1981 |
| Dr. James J. Collins Ph.D. | Co-Founder & Member of Scientific Advisory Board | 1966 |
| Mr. Michael Jensen | Chief Financial Officer | NA |
| Dr. David L. Hava Ph.D. | Chief Scientific Officer | 1975 |
| Dr. Elizabeth Wolffe | Head of Investor Relations & Corp. Communications | NA |
| Mr. Brendan St. Amant | Gen. Counsel & Corp. Sec. | NA |
| Mr. Ajay Munshi | VP of Corp. Devel. | NA |
| Mr. Adam Thomas | Chief People Officer | NA |
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