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C4 Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights
Thu 07 Aug 25, 11:00 AMC4 Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights
Wed 07 May 25, 11:00 AM| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -104.87300M | -105.18500M | -131.21300M | -128.17500M | -83.89200M |
| Minority interest | - | - | - | - | - |
| Net income | -104.99400M | -105.31600M | -132.49300M | -126.49900M | -86.03700M |
| Selling general administrative | 36.20M | 42.12M | 42.08M | 42.79M | 33.25M |
| Selling and marketing expenses | - | - | 7.74M | - | - |
| Gross profit | 27.97M | 35.58M | 13.02M | 31.10M | 45.78M |
| Reconciled depreciation | 1.96M | 1.82M | 1.97M | 1.68M | 1.49M |
| Ebit | -104.87300M | -105.18500M | -129.84000M | -129.53400M | -82.13400M |
| Ebitda | -102.91400M | -103.36700M | -122.10300M | -125.95900M | -80.25500M |
| Depreciation and amortization | 1.96M | 1.82M | 7.74M | 3.58M | 1.88M |
| Non operating income net other | - | - | - | -2.00300M | -2.54600M |
| Operating income | -104.48900M | -119.61400M | -139.03100M | -129.53400M | -82.13400M |
| Other operating expenses | 140.44M | 155.20M | 159.79M | 160.63M | 127.92M |
| Interest expense | - | 0.00000M | 1.37M | 2.22M | 2.15M |
| Tax provision | 0.12M | 0.13M | 1.28M | - | 0.00000M |
| Interest income | 10.35M | 14.43M | 8.57M | 3.58M | 0.39M |
| Net interest income | 10.35M | 14.43M | 6.60M | 1.36M | -1.75800M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | 0.12M | 0.13M | 1.28M | -1.67600M | 2.15M |
| Total revenue | 35.95M | 35.58M | 20.76M | 31.10M | 45.78M |
| Total operating expenses | 132.46M | 155.20M | 152.05M | 160.63M | 127.92M |
| Cost of revenue | 7.97M | 7.89M | 7.74M | - | - |
| Total other income expense net | -0.38400M | 14.43M | 7.82M | 1.36M | -1.75800M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | -104.99400M | -105.31600M | -134.92400M | -128.17500M | -83.89200M |
| Net income applicable to common shares | - | - | - | -128.17500M | -83.89200M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 359.07M | 349.60M | 376.45M | 430.84M | 506.76M |
| Intangible assets | - | - | - | - | - |
| Earning assets | - | - | - | - | - |
| Other current assets | 7.17M | 9.76M | 5.71M | 9.93M | 10.69M |
| Total liab | 102.49M | 133.62M | 130.34M | 141.61M | 117.16M |
| Total stockholder equity | 256.59M | 215.99M | 246.11M | 289.23M | 389.61M |
| Deferred long term liab | - | - | - | - | 24.37M |
| Other current liab | 13.31M | 19.36M | 20.63M | 2.87M | 13.61M |
| Common stock | 0.00900M | 0.00700M | 0.00600M | 0.00500M | 0.00500M |
| Capital stock | 0.00900M | 0.00700M | 0.00600M | 0.00500M | 0.00500M |
| Retained earnings | -738.69300M | -633.69900M | -528.38300M | -395.89000M | -267.71500M |
| Other liab | - | - | - | 16.89M | 24.37M |
| Good will | - | - | - | - | - |
| Other assets | - | - | - | 4.80M | 3.82M |
| Cash | 74.60M | 55.50M | 126.59M | 29.75M | 76.12M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 33.03M | 45.18M | 42.77M | 44.55M | 51.25M |
| Current deferred revenue | 12.49M | 18.71M | 15.47M | 33.51M | 31.80M |
| Net debt | -14.62100M | 10.26M | -55.61400M | 57.40M | -33.24500M |
| Short term debt | 6.37M | 5.77M | 5.22M | 6.99M | 1.33M |
| Short long term debt | - | - | - | 2.29M | - |
| Short long term debt total | 59.98M | 65.76M | 70.98M | 87.15M | 42.88M |
| Other stockholder equity | 995.22M | 849.62M | 774.62M | 689.26M | 658.09M |
| Property plant equipment | - | - | - | 7.40M | 3.11M |
| Total current assets | 258.11M | 257.77M | 271.19M | 287.56M | 325.69M |
| Long term investments | 48.56M | 22.36M | 28.01M | 60.96M | 142.20M |
| Net tangible assets | - | - | - | 289.23M | 389.61M |
| Short term investments | 173.93M | 189.41M | 127.09M | 246.40M | 233.16M |
| Net receivables | 2.40M | 3.10M | 11.80M | 1.47M | 5.72M |
| Long term debt | - | - | - | 9.20M | 10.77M |
| Inventory | - | - | - | -60.96200M | - |
| Accounts payable | 0.86M | 1.33M | 1.45M | 1.17M | 4.51M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | 0.05M | 0.05M | -0.12700M | -4.13700M | -0.77500M |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | - | - | 0.00500M | 0.00500M |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | - | - | -395.89000M | -267.71500M |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 55.69M | 6.10M | 2.72M | 4.80M | 3.82M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 100.97M | 91.83M | 105.26M | 143.28M | 181.08M |
| Capital lease obligations | 59.98M | 65.76M | 70.98M | 75.67M | 32.11M |
| Long term debt total | - | - | - | 9.20M | 10.77M |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -7.99400M | -51.27000M | 135.69M | 58.42M | -188.05900M |
| Change to liabilities | - | - | - | -20.90400M | -21.85400M |
| Total cashflows from investing activities | -8.60100M | -51.27000M | 158.35M | 58.42M | -189.33600M |
| Net borrowings | - | 0.00000M | -12.50000M | - | - |
| Total cash from financing activities | 126.40M | 45.34M | 45.49M | 1.15M | 171.40M |
| Change to operating activities | - | - | - | 4.96M | -2.62700M |
| Net income | -104.99400M | -105.31600M | -132.49300M | -128.17500M | -83.89200M |
| Change in cash | 19.10M | -71.09100M | 97.00M | -46.37000M | -104.90100M |
| Begin period cash flow | 58.94M | 130.03M | 33.03M | 79.40M | 184.30M |
| End period cash flow | 78.05M | 58.94M | 130.03M | 33.03M | 79.40M |
| Total cash from operating activities | -98.69400M | -65.15700M | -106.83800M | -105.93900M | -86.96500M |
| Issuance of capital stock | 126.21M | 44.37M | 57.67M | 0.00000M | 169.47M |
| Depreciation | 1.96M | 1.82M | 1.88M | 1.68M | 1.49M |
| Other cashflows from investing activities | - | - | - | - | - |
| Dividends paid | - | - | - | - | - |
| Change to inventory | - | - | - | - | -2.62700M |
| Change to account receivables | 0.70M | 8.70M | -10.32700M | 4.24M | -1.23200M |
| Sale purchase of stock | -0.19300M | -0.19400M | -0.11000M | 0.78M | 2.04M |
| Other cashflows from financing activities | 0.27M | 1.16M | 0.43M | 0.37M | 1.94M |
| Change to netincome | - | - | - | 30.02M | 21.51M |
| Capital expenditures | 0.61M | 0.18M | 1.71M | 5.50M | 1.28M |
| Change receivables | - | - | - | 4.24M | -1.23200M |
| Cash flows other operating | - | - | - | 5.78M | -5.58900M |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | - | - | - | -46.37000M | -104.90100M |
| Change in working capital | -29.28200M | 7.65M | -6.93800M | -16.77900M | -30.09000M |
| Stock based compensation | 19.10M | 29.66M | 27.23M | 30.02M | 21.51M |
| Other non cash items | 14.52M | 1.03M | 3.48M | 7.32M | 2.13M |
| Free cash flow | -99.30100M | -65.33700M | -108.54600M | -111.43500M | -88.24200M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to Revenue (x) | Enterprise Value to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| CCCC C4 Therapeutics Inc |
0.10 2.43% | 4.22 | - | - | 8.12 | 1.14 | 2.86 | -0.4171 |
| NVO Novo Nordisk A/S |
1.54 3.36% | 47.42 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
- -% | 45.00 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
1.63 0.35% | 468.42 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
5.53 0.90% | 618.03 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins. Its lead product candidate is Cemsidomide, an orally bioavailable monodac targeting IKZF1 and IKZF3, or IKZF1/3 to address a need across multiple lines of therapy in multiple myeloma, which has competed its phase 1. The company is also developing oncology product candidate, CFT8919, an orally bioavailable, allosteric, mutant-selective bidac degrader of epidermal growth factor receptor, with an L858R mutation in non-small cell lung cancer; and new degraders focused on inflammation, neuroinflammation, and neurodegeneration. It has strategic collaborations F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., Betta Pharmaceuticals Co. Ltd., and Merck KGAA. Additionally, it has a collaboration agreement with Roche Holding AG for the development of Degrader-Antibody Conjugates for cancer treatment. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
490 Arsenal Way, Watertown, MA, United States, 02472
| Name | Title | Year Born |
|---|---|---|
| Mr. Andrew J. Hirsch | CEO, Pres & Director | 1971 |
| Dr. Kenneth C. Anderson M.D., Ph.D. | Co-Founder, Independent Director & Member of Scientific Advisory Board | 1951 |
| Ms. Lauren A. White | Chief Financial Officer | NA |
| Dr. Stewart Fisher | Chief Scientific Officer | 1967 |
| Ms. Jolie M. Siegel J.D. | Chief Legal Officer | 1977 |
| Dr. Adam S. Crystal M.D., Ph.D. | Chief Medical Officer | 1977 |
| Dr. Nathanael S. Gray Ph.D. | Co-Founder & Member of Scientific Advisory Board | NA |
| Ms. Kendra Adams | Sr. VP of Communications & Investor Relations | NA |
| Kristina Zambouras | Director of HR | NA |
| Ms. Kelly Schick | Chief People Officer | NA |
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