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Last update at 2026-06-23T20:20:00Z
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Biotech Alert: Searches spiking for these stocks today
Fri 14 Mar 25, 04:15 PMState Street Corp's Strategic Reduction in Cabaletta Bio Inc Holdings
Thu 17 Oct 24, 07:06 PM| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Income before tax | -167.85600M | -115.86400M | -67.67500M | -52.97500M | -46.28900M |
| Minority interest | - | - | - | - | - |
| Net income | -167.85600M | -115.86400M | -67.67500M | -51.81100M | -45.53200M |
| Selling general administrative | 29.57M | 27.94M | 19.24M | 14.84M | 13.82M |
| Selling and marketing expenses | - | - | 1.43M | - | - |
| Gross profit | -1.64600M | -4.81300M | -1.42600M | - | - |
| Reconciled depreciation | 1.65M | 1.71M | 1.43M | 1.18M | 0.73M |
| Ebit | -172.24100M | -115.11600M | -67.67500M | -55.31700M | -47.04600M |
| Ebitda | -170.59500M | -110.30300M | -66.24900M | -54.13900M | -46.31300M |
| Depreciation and amortization | 1.65M | 4.81M | 1.43M | 1.18M | 0.73M |
| Non operating income net other | - | - | - | 1.16M | - |
| Operating income | -172.24100M | -125.14100M | -74.66000M | -54.13900M | -46.31300M |
| Other operating expenses | 172.24M | 125.14M | 74.66M | 54.14M | 46.31M |
| Interest expense | 2.00M | 0.75M | 0.00000M | -1.17800M | 0.73M |
| Tax provision | - | - | - | - | - |
| Interest income | 6.03M | 10.03M | 6.99M | 1.16M | 0.02M |
| Net interest income | 4.03M | 9.28M | 6.99M | 1.16M | 0.02M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | - | - | - | -1.16400M | -0.75700M |
| Total revenue | 0.00000M | 0.00000M | 0.00000M | 0.00000M | 0.00000M |
| Total operating expenses | 170.59M | 120.33M | 73.23M | 54.14M | 46.31M |
| Cost of revenue | 1.65M | 4.81M | 1.43M | - | - |
| Total other income expense net | 4.38M | 9.28M | 6.99M | 1.16M | 0.02M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | -167.85600M | -115.86400M | -67.67500M | -52.97500M | -46.28900M |
| Net income applicable to common shares | - | - | - | -52.97500M | -46.28900M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Total assets | 165.08M | 185.05M | 253.65M | 116.97M | 126.34M |
| Intangible assets | - | - | - | - | - |
| Earning assets | - | - | - | - | - |
| Other current assets | 5.27M | 2.71M | 3.24M | 2.29M | 2.32M |
| Total liab | 53.03M | 32.71M | 17.45M | 12.45M | 8.38M |
| Total stockholder equity | 112.05M | 152.34M | 236.20M | 104.52M | 117.96M |
| Deferred long term liab | - | - | - | - | - |
| Other current liab | 19.30M | 12.19M | 7.89M | 4.85M | 6.05M |
| Common stock | 0.00100M | 0.00100M | - | - | - |
| Capital stock | 0.00100M | 0.00100M | 0.00000M | 0.00000M | 0.00000M |
| Retained earnings | -516.95700M | -349.10100M | -233.23700M | -165.56200M | -112.58700M |
| Other liab | - | - | - | - | - |
| Good will | - | - | - | - | - |
| Other assets | - | -3.93800M | 0.00000M | 0.56M | 0.36M |
| Cash | 82.98M | 163.96M | 193.24M | 81.61M | 122.22M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 50.15M | 27.09M | 15.99M | 9.49M | 8.38M |
| Current deferred revenue | - | - | - | - | - |
| Net debt | -55.88400M | -148.36200M | -188.22000M | -76.46900M | -122.22200M |
| Short term debt | 24.22M | 9.97M | 3.56M | 2.18M | - |
| Short long term debt | - | - | - | - | - |
| Short long term debt total | 27.10M | 15.60M | 5.02M | 5.14M | - |
| Other stockholder equity | 628.98M | 501.44M | 469.40M | 270.13M | 230.54M |
| Property plant equipment | - | - | - | 2.58M | 1.44M |
| Total current assets | 138.87M | 166.68M | 244.49M | 108.83M | 124.54M |
| Long term investments | - | - | - | - | - |
| Net tangible assets | - | - | - | 104.52M | 116.61M |
| Short term investments | 50.62M | 0.00000M | 48.01M | 24.94M | - |
| Net receivables | - | - | - | - | - |
| Long term debt | - | - | - | - | - |
| Inventory | - | - | - | - | - |
| Accounts payable | 6.64M | 4.92M | 4.55M | 2.46M | 2.33M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | 0.03M | - | 0.04M | -0.04700M | - |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | - | - | - | - |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | - | - | -165.56200M | - |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 5.16M | 6.23M | 1.71M | 0.56M | 0.36M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 26.21M | 22.31M | 9.16M | 8.13M | 1.79M |
| Capital lease obligations | 27.10M | 15.60M | 5.02M | 5.14M | - |
| Long term debt total | - | - | - | - | - |
| Breakdown | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
| Investments | -49.03700M | 47.29M | -22.45100M | -24.76400M | 7.17M |
| Change to liabilities | - | - | - | -1.21300M | 0.97M |
| Total cashflows from investing activities | -50.26600M | 47.29M | -22.45100M | -27.21700M | 6.00M |
| Net borrowings | -6.26100M | -0.89700M | 0.00000M | - | - |
| Total cash from financing activities | 100.35M | 11.68M | 187.63M | 32.98M | 48.90M |
| Change to operating activities | - | - | - | -4.27100M | 4.61M |
| Net income | -167.85600M | -115.86400M | -67.67500M | -52.97500M | -46.28900M |
| Change in cash | -80.98000M | -29.27600M | 111.63M | -40.61500M | 20.79M |
| Begin period cash flow | 163.96M | 193.24M | 81.61M | 122.22M | 101.43M |
| End period cash flow | 82.98M | 163.96M | 193.24M | 81.61M | 122.22M |
| Total cash from operating activities | -131.08000M | -88.22200M | -53.54900M | -46.38000M | -34.10900M |
| Issuance of capital stock | 106.30M | 10.88M | 185.20M | 32.85M | 48.32M |
| Depreciation | 1.65M | 1.71M | 1.43M | 1.18M | 0.73M |
| Other cashflows from investing activities | - | - | - | - | - |
| Dividends paid | - | - | - | - | - |
| Change to inventory | - | - | - | - | - |
| Change to account receivables | - | - | - | - | - |
| Sale purchase of stock | 0.29M | 0.27M | 0.11M | 0.08M | 0.07M |
| Other cashflows from financing activities | 100.35M | 1.70M | 2.43M | 0.05M | 0.58M |
| Change to netincome | - | - | - | 6.90M | 5.87M |
| Capital expenditures | 1.23M | 2.21M | 0.69M | 2.45M | 1.17M |
| Change receivables | - | - | - | - | - |
| Cash flows other operating | - | - | - | -0.72900M | - |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | - | - | - | -40.61500M | - |
| Change in working capital | -0.37900M | 1.61M | 0.10M | -4.29900M | 5.58M |
| Stock based compensation | 20.94M | 19.46M | 11.34M | 6.90M | 5.80M |
| Other non cash items | 14.57M | 4.86M | 1.26M | 2.82M | 0.06M |
| Free cash flow | -132.30900M | -90.43300M | -54.23600M | -48.83300M | -35.27500M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to EBITDA (x) | |
|---|---|---|---|---|---|---|---|---|
| CABA Cabaletta Bio Inc |
0.01 0.33% | 3.02 | - | - | - | 3.28 | -3.4401 | |
| NVO Novo Nordisk A/S |
1.54 3.36% | 47.42 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
- -% | 45.00 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
1.63 0.35% | 468.42 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
5.53 0.90% | 618.03 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. Its lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, non-renal systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis. The company also develops DSG3-CAART, a CAAR T cell therapy that is in Phase 1 clinical trial for the treatment of mucosal PV; and MuSK-CAART, an investigational cell therapy in Phase 1 trial for treating patients with anti-muscle-specific kinase (MuSK) antibody positive myasthenia gravis. It has collaborations with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; Autolus Holdings (UK) Limited; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.
2929 Arch Street, Philadelphia, PA, United States, 19104
| Name | Title | Year Born |
|---|---|---|
| Dr. Steven A. Nichtberger M.D. | Co-Founder, Chairman, CEO & Pres | 1961 |
| Dr. Gwendolyn K. Binder Ph.D. | Pres of Science & Technology | 1975 |
| Dr. David J. Chang FACR, M.D., M.P.H. | Chief Medical Officer | 1963 |
| Dr. Michael C. Milone M.D., Ph.D. | Co-Founder & Co-Chair of Scientific Advisory Board | NA |
| Dr. Aimee Payne M.D., Ph.D. | Co-Founder & Co-Chair of Scientific Advisory Board | NA |
| Mr. Anup Marda M.B.A. | Chief Financial Officer | 1977 |
| Dr. Samik Basu M.D. | Chief Scientific Officer | NA |
| Mr. Michael Gerard J.D. | Gen. Counsel & Sec. | 1980 |
| Ms. Heather Harte-Hall M.Sc. | Chief Compliance Officer | NA |
| Ms. Martha O'Connor | Chief HR Officer | NA |
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