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Last update at 2024-09-11T10:46:09.530491Z
Source: TradingView
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -55.43200M | -50.42000M | -27.94600M | -41.85200M | -36.85300M |
| Minority interest | - | - | - | - | - |
| Net income | -57.76200M | -50.33300M | -27.94000M | -42.53400M | -36.48700M |
| Selling general administrative | 17.97M | 14.56M | 10.90M | 9.47M | 8.36M |
| Selling and marketing expenses | - | - | - | - | - |
| Gross profit | 30.06M | 23.44M | 9.34M | 1.74M | 0.70M |
| Reconciled depreciation | 0.60M | 0.62M | 0.58M | 0.47M | 0.39M |
| Ebit | -58.14700M | -49.85900M | -28.74900M | -43.57400M | -35.71900M |
| Ebitda | -54.95600M | -49.60400M | -27.17100M | -41.51400M | -35.33100M |
| Depreciation and amortization | 3.19M | 0.26M | 1.58M | 2.06M | 0.39M |
| Non operating income net other | 3.19M | 0.26M | 1.58M | 2.06M | 1.30M |
| Operating income | -58.14700M | -49.85900M | -28.74900M | -43.57400M | -37.83000M |
| Other operating expenses | 88.21M | 73.30M | 38.08M | 45.31M | 37.33M |
| Interest expense | 0.48M | 0.82M | 0.78M | 0.34M | 0.32M |
| Tax provision | 2.33M | -0.08700M | -0.00600M | 0.00000M | -0.36600M |
| Interest income | 3.29M | 0.26M | 0.24M | 1.25M | 1.30M |
| Net interest income | 2.81M | -0.55700M | -0.53000M | 0.91M | 0.98M |
| Extraordinary items | - | - | - | - | - |
| Non recurring | - | - | - | - | - |
| Other items | - | - | - | - | - |
| Income tax expense | 2.33M | -0.08700M | -0.00600M | 0.68M | -0.36600M |
| Total revenue | 30.06M | 23.44M | 9.34M | 1.74M | 0.70M |
| Total operating expenses | 88.21M | 73.30M | 38.08M | 45.31M | 37.33M |
| Cost of revenue | - | - | - | - | 28.97M |
| Total other income expense net | 2.71M | -0.56100M | 0.80M | 1.72M | -1.20300M |
| Discontinued operations | - | - | - | - | - |
| Net income from continuing ops | -57.76200M | -50.33300M | -27.94000M | -41.85200M | -36.48700M |
| Net income applicable to common shares | -57.76200M | -50.33300M | -27.94000M | -41.85200M | -36.48700M |
| Preferred stock and other adjustments | - | - | - | - | - |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 381.81M | 286.69M | 255.90M | 144.09M | 54.09M |
| Intangible assets | - | - | - | - | - |
| Earning assets | - | - | - | - | - |
| Other current assets | 1.87M | 2.96M | 4.71M | 1.52M | 1.78M |
| Total liab | 53.87M | 107.27M | 135.00M | 81.93M | 24.62M |
| Total stockholder equity | 327.94M | 179.42M | 120.90M | 62.16M | 29.47M |
| Deferred long term liab | - | - | - | - | - |
| Other current liab | 21.19M | 14.00M | 9.42M | 5.78M | 5.29M |
| Common stock | 0.06M | 0.05M | 0.03M | 0.02M | 0.02M |
| Capital stock | 0.06M | 0.05M | 0.03M | 0.02M | 0.02M |
| Retained earnings | -256.14500M | -223.96100M | -166.19900M | -115.86600M | -87.92600M |
| Other liab | - | 39.19M | 50.83M | 21.35M | - |
| Good will | - | - | - | - | - |
| Other assets | 0.00000M | 0.41M | 4.96M | 35.20M | 0.25M |
| Cash | 43.92M | 13.38M | 67.91M | 34.96M | 16.12M |
| Cash and equivalents | - | - | - | - | - |
| Total current liabilities | 41.98M | 58.00M | 69.78M | 41.17M | 8.68M |
| Current deferred revenue | 16.29M | 35.57M | 51.77M | 31.63M | 1.44M |
| Net debt | -34.00700M | 0.84M | -48.27900M | -12.36100M | 0.23M |
| Short term debt | 0.91M | 4.14M | 5.24M | 3.18M | 0.42M |
| Short long term debt | - | 3.38M | 4.62M | 2.53M | 0.42M |
| Short long term debt total | 9.91M | 14.22M | 19.63M | 22.60M | 16.36M |
| Other stockholder equity | 583.63M | 404.46M | 287.35M | 177.95M | 117.37M |
| Property plant equipment | - | 1.58M | 10.55M | 11.19M | 1.55M |
| Total current assets | 330.03M | 240.99M | 192.01M | 107.10M | 42.30M |
| Long term investments | 40.56M | 35.48M | 52.87M | 25.55M | - |
| Net tangible assets | - | 179.42M | 120.90M | 62.16M | 29.47M |
| Short term investments | 283.49M | 224.26M | 94.40M | 70.62M | 24.40M |
| Net receivables | 0.75M | 0.71M | 25.32M | 0.39M | 0.69M |
| Long term debt | - | - | 3.38M | 7.60M | 4.51M |
| Inventory | -0.16700M | -0.31700M | -0.32300M | -0.38800M | -0.68600M |
| Accounts payable | 3.59M | 4.29M | 3.35M | 0.58M | 1.54M |
| Total permanent equity | - | - | - | - | - |
| Noncontrolling interest in consolidated entity | - | - | - | - | - |
| Temporary equity redeemable noncontrolling interests | - | - | - | - | - |
| Accumulated other comprehensive income | 0.40M | -1.12100M | -0.27300M | 0.05M | 0.01000M |
| Additional paid in capital | - | - | - | - | - |
| Common stock total equity | - | 0.05M | 0.03M | 0.02M | 0.02M |
| Preferred stock total equity | - | - | - | - | - |
| Retained earnings total equity | - | -223.96100M | -166.19900M | -115.86600M | -87.92600M |
| Treasury stock | - | - | - | - | - |
| Accumulated amortization | - | - | - | - | - |
| Non currrent assets other | 0.27M | 0.25M | 11.02M | 0.25M | 0.25M |
| Deferred long term asset charges | - | - | - | - | - |
| Non current assets total | 51.78M | 45.69M | 63.89M | 36.99M | 11.79M |
| Capital lease obligations | 9.91M | 10.84M | 11.63M | 12.47M | 11.43M |
| Long term debt total | - | - | 3.38M | 7.60M | 4.51M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | -112.93600M | -52.36200M | -72.81900M | 17.58M | 32.36M |
| Change to liabilities | 5.56M | 30.60M | 51.05M | 0.82M | 5.42M |
| Total cashflows from investing activities | -113.34800M | -52.48000M | -72.81900M | 16.76M | 32.12M |
| Net borrowings | -4.80000M | -2.40000M | 5.00M | 0.64M | -1.00000M |
| Total cash from financing activities | 102.69M | 100.76M | 61.38M | 24.25M | -0.99100M |
| Change to operating activities | 1.83M | -3.34300M | 1.89M | 0.95M | 0.07M |
| Net income | -57.76200M | -50.33300M | -27.94000M | -41.85200M | -36.48700M |
| Change in cash | -54.53100M | 32.95M | 18.70M | 5.67M | 2.71M |
| Begin period cash flow | 68.16M | 35.21M | 16.51M | 10.84M | 8.13M |
| End period cash flow | 13.63M | 68.16M | 35.21M | 16.51M | 10.84M |
| Total cash from operating activities | -43.75400M | -15.24800M | 30.08M | -35.34600M | -28.41600M |
| Issuance of capital stock | 106.72M | 102.66M | 56.26M | 23.60M | 0.00000M |
| Depreciation | 0.60M | 0.62M | 0.58M | 0.47M | 0.39M |
| Other cashflows from investing activities | - | - | - | 17.58M | 0.25M |
| Dividends paid | - | - | - | - | - |
| Change to inventory | - | - | - | - | - |
| Change to account receivables | 24.60M | 24.60M | 24.60M | 24.60M | - |
| Sale purchase of stock | 107.49M | 103.16M | 56.38M | 23.61M | 0.00900M |
| Other cashflows from financing activities | 0.77M | 0.50M | 5.12M | 1.99M | 0.00900M |
| Change to netincome | 9.79M | 7.21M | 4.51M | 3.20M | 3.38M |
| Capital expenditures | 0.41M | 0.12M | 0.80M | 0.82M | 0.49M |
| Change receivables | 24.60M | - | - | - | - |
| Cash flows other operating | -26.01300M | 21.29M | 53.43M | 2.38M | -0.44200M |
| Exchange rate changes | - | - | - | - | - |
| Cash and cash equivalents changes | -54.41300M | 33.04M | 18.65M | 5.67M | 2.71M |
| Change in working capital | 4.19M | 27.04M | 52.94M | 3.20M | 4.67M |
| Stock based compensation | 9.65M | 6.24M | 4.14M | 3.04M | 2.31M |
| Other non cash items | -0.47500M | 0.27M | 0.26M | 0.14M | 1.01M |
| Free cash flow | -44.16600M | -15.36600M | 29.28M | -36.16700M | -28.91100M |
Sector: Healthcare Industry: Biotechnology
| Company | Change (USD) | Price (USD) | Trailing PE (x) | Forward PE (x) | Price Sales TTM (x) | Price to Book Value (x) | Enterprise Value to Revenue (x) | Enterprise Value to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| ALPN Alpine Immune Sciences Inc |
- -% | - | - | - | 71.68 | 12.87 | 66.29 | -124.2599 |
| NVO Novo Nordisk A/S |
-2.38 3.09% | 74.64 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| NONOF Novo Nordisk A/S |
-3.16 4.04% | 75.15 | 41.06 | 31.25 | 2.08 | 33.11 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-2.28 0.51% | 448.63 | 29.67 | 24.33 | 10.38 | 5.83 | 9.33 | 20.00 |
| REGN Regeneron Pharmaceuticals Inc |
-3.845 0.74% | 518.84 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
Alpine Immune Sciences, Inc. operates as a clinical-stage biopharmaceutical company. It focuses on the discovery and development of immunotherapies through protein engineering technologies for treating autoimmune and inflammatory diseases. The company's product pipeline includes Povetacicept, a dual B cell cytokine antagonist, which is in Phase 2 clinical trial for the treatment of multiple autoimmune and inflammatory diseases; and Acazicolcept, a dual inhibitor of the CD28 and ICOS T cell costimulatory pathways that is in preclinical trial for the treatment of systemic lupus erythematosus. It is also developing RUBY-3 that has completed Phase 1 clinical trial for the treatment of glomerulonephritis; and RUBY-4, which has completed Phase 1 clinical trial for the treatment of cytopenias. The company was incorporated in 2007 and is headquartered in Seattle, Washington. As of May 20, 2024, Alpine Immune Sciences, Inc. operates as a subsidiary of Vertex Pharmaceuticals Incorporated.
188 East Blaine Street, Seattle, WA, United States, 98102
| Name | Title | Year Born |
|---|---|---|
| Dr. Mitchell H. Gold M.D. | Exec. Chairman & CEO | 1968 |
| Dr. Stanford Peng M.D., Ph.D. | Pres and Head of R&D | 1971 |
| Mr. Paul Rickey | Sr. VP, CFO, Treasurer & Sec. | 1979 |
| Dr. Wayne R. Gombotz | Chief Technology Officer | 1959 |
| Temre Johnson | Head of IR & Corp. Communications | NA |
| Dr. Remy Durand Ph.D. | Chief Bus. Officer | NA |
| Dr. Pamela Holland Ph.D. | Sr. VP of Research | NA |
| Dr. Andrew Seth Sandler M.D. | Chief Medical Officer | 1965 |
| Dr. Mitchell H. Gold M.D. | Executive Chairman & CEO | 1968 |
| Dr. Stanford Peng M.D., Ph.D. | President and Head of Research & Development | 1971 |
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