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Adverum Biotechnologies, Inc., a clinical-stage company, develops gene therapy product candidates to treat ocular diseases. Its lead product candidate is ixoberogene soroparvovec (ADVM-022), a single intravitreal injection gene therapy candidate used for the treatment of patients with wet age-related macular degeneration and diabetic macular edema which is in phase 2 clinical trials. The company is developing ADVM-062 (AAV.7m8-L-opsin), a novel gene therapy product candidate for the treatment of blue cone monochromacy via a single IVT injection. Adverum Biotechnologies, Inc. has license and collaboration agreements with University of California; GenSight Biologics; Lexeo Therapeutics; and Virovek, Inc. The company was formerly known as Avalanche Biotechnologies, Inc. and changed its name to Adverum Biotechnologies, Inc. in May 2016. Adverum Biotechnologies, Inc. was incorporated in 2006 and is headquartered in Redwood City, California.
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| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Income before tax | -154.46M | -145.54M | -116.39M | -64.49M | -73.88M |
| Net income | -154.54M | -145.54M | -117.51M | -64.49M | -72.63M |
| Selling general administrative | 57.86M | 64.44M | 44.64M | 28.38M | 24.56M |
| Gross profit | - | 7.50M | - | 0.25M | 1.61M |
| Reconciled depreciation | 6.53M | 4.64M | 4.16M | 1.57M | 1.75M |
| Ebit | -157.13M | -146.12M | -117.95M | -68.55M | -68.08M |
| Ebitda | -150.61M | -141.48M | -113.79M | -66.97M | -66.33M |
| Depreciation and amortization | 6.53M | 4.64M | 4.16M | 1.57M | 1.75M |
| Non operating income net other | - | 0.15M | 1.65M | 4.09M | 4.37M |
| Operating income | -157.13M | -146.12M | -117.95M | -68.55M | -78.08M |
| Other operating expenses | 157.13M | 153.62M | 117.95M | 68.80M | 74.69M |
| Interest expense | -2.67M | 0.58M | 1.56M | 0.00M | 0.00M |
| Tax provision | 0.07M | 0.00M | 1.11M | 0.00M | -1.25M |
| Non recurring | - | - | - | - | 5.00M |
| Income tax expense | 0.07M | -0.58M | 1.11M | -4.06M | -1.25M |
| Total revenue | 0.00M | 7.50M | 0.00M | 0.25M | 1.61M |
| Total operating expenses | 157.13M | 153.62M | 117.95M | 68.80M | 74.69M |
| Cost of revenue | - | - | - | 40.42M | 50.13M |
| Total other income expense net | 2.67M | 0.58M | 1.56M | 4.06M | -0.80M |
| Net income from continuing ops | -154.54M | -145.54M | -117.51M | -64.49M | -72.63M |
| Net income applicable to common shares | -154.54M | -145.54M | -117.51M | -64.49M | -72.63M |
| Breakdown | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 173.01M | 308.37M | 439.73M | 482.57M | 222.73M |
| Other current assets | 6.25M | 5.01M | 6.25M | 4.71M | 9.84M |
| Total liab | 89.54M | 126.85M | 123.54M | 48.22M | 47.77M |
| Total stockholder equity | 83.47M | 181.52M | 316.19M | 434.35M | 174.96M |
| Other current liab | 12.48M | 16.77M | 2.02M | 1.32M | 2.64M |
| Common stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Capital stock | 0.01M | 0.01M | 0.01M | 0.01M | 0.01M |
| Retained earnings | -919.78M | -802.61M | -648.08M | -502.54M | -385.03M |
| Other liab | - | 1.05M | 1.11M | 1.11M | 0.05M |
| Other assets | - | 3.92M | 3.52M | 1.03M | 1.01M |
| Cash | 75.00M | 68.43M | 34.20M | 62.42M | 65.90M |
| Total current liabilities | 24.91M | 32.25M | 21.32M | 20.87M | 19.41M |
| Current deferred revenue | 0.10M | - | 16.03M | 12.26M | 8.63M |
| Net debt | 0.04M | 38.37M | 68.80M | -31.72M | -33.65M |
| Short term debt | 10.41M | 13.24M | 1.89M | 4.47M | 4.03M |
| Short long term debt | - | - | - | - | 0.10M |
| Short long term debt total | 75.04M | 106.80M | 102.99M | 30.71M | 32.25M |
| Other stockholder equity | 1003.71M | 985.65M | 964.97M | 937.13M | 560.70M |
| Property plant equipment | - | 113.86M | 33.06M | 27.73M | 24.88M |
| Total current assets | 102.77M | 190.59M | 317.14M | 434.44M | 175.87M |
| Net tangible assets | - | 181.52M | 316.19M | 434.35M | 174.96M |
| Short term investments | 21.53M | 117.16M | 270.99M | 367.31M | 100.14M |
| Net receivables | - | 0.00M | 5.71M | - | - |
| Long term debt | - | - | - | - | 0.10M |
| Accounts payable | 1.92M | 2.24M | 1.39M | 2.81M | 4.10M |
| Accumulated other comprehensive income | -0.47M | -1.53M | -0.71M | -0.26M | -0.72M |
| Common stock total equity | - | - | 0.01M | 0.01M | 0.01M |
| Retained earnings total equity | - | - | -648.08M | -502.54M | -385.03M |
| Non currrent assets other | 1.23M | 3.92M | 3.52M | 1.03M | 1.01M |
| Non current assets total | 70.24M | 117.78M | 122.58M | 48.13M | 46.86M |
| Capital lease obligations | 75.04M | 106.80M | 102.99M | 30.71M | 32.25M |
| Breakdown | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
|---|---|---|---|---|---|
| Type | yearly | yearly | yearly | yearly | yearly |
| Date | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 |
| Investments | 141.72M | 93.83M | -268.32M | -48.83M | 70.25M |
| Change to liabilities | 0.84M | 1.66M | 6.85M | 1.26M | 0.15M |
| Total cashflows from investing activities | 141.72M | 78.71M | -280.17M | -68.07M | 69.44M |
| Net borrowings | - | -0.24M | -0.06M | -0.11M | -0.07M |
| Total cash from financing activities | 0.61M | 2.40M | 355.99M | 28.19M | 69.95M |
| Change to operating activities | 19.04M | 5.67M | 11.14M | 5.71M | 0.65M |
| Net income | -154.54M | -145.54M | -117.51M | -64.49M | -72.63M |
| Change in cash | 34.24M | -26.73M | -3.47M | -89.05M | 85.43M |
| Begin period cash flow | 36.70M | 63.42M | 66.90M | 155.95M | 70.52M |
| End period cash flow | 70.93M | 36.70M | 63.42M | 66.90M | 155.95M |
| Total cash from operating activities | -108.09M | -107.83M | -79.29M | -49.17M | -53.96M |
| Issuance of capital stock | 0.00M | 1.69M | 344.30M | 25.89M | 70.19M |
| Depreciation | 6.53M | 4.64M | 4.16M | 1.57M | 1.75M |
| Other cashflows from investing activities | - | - | - | -48.83M | 70.25M |
| Change to account receivables | - | - | - | - | 0.00M |
| Sale purchase of stock | - | 2.64M | 358.09M | 29.77M | 71.22M |
| Other cashflows from financing activities | 0.60M | 0.95M | 11.74M | 2.41M | -0.06M |
| Change to netincome | 20.03M | 26.23M | 20.79M | 9.94M | 18.41M |
| Capital expenditures | 11.82M | 15.12M | 11.84M | 19.25M | 0.81M |
| Cash flows other operating | - | 2.40M | 5.88M | 3.80M | -1.76M |
| Cash and cash equivalents changes | - | -26.73M | -3.47M | -89.05M | 85.43M |
| Change in working capital | 19.89M | 4.06M | 12.73M | 5.06M | -1.62M |
| Stock based compensation | 20.08M | 25.19M | 20.39M | 9.90M | 13.43M |
| Other non cash items | -0.05M | -0.03M | 0.07M | 0.06M | 6.35M |
| Free cash flow | -119.91M | -122.95M | -91.14M | -68.42M | -54.77M |
Sector: Healthcare Industry: Biotechnology
|
Stock Name
|
Change
(USD) |
Price
(USD) |
Trailing
PE (x) |
Forward
PE (x) |
Price Sales
TTM (x) |
Price to Book Value (x)
|
Enterprise Value
to Revenue (x) |
Enterprise Value
to EBITDA (x) |
|---|---|---|---|---|---|---|---|---|
| NVO Novo Nordisk A/S |
0.08 0.20% |
39.13 | 41.58 | 31.15 | 2.13 | 32.99 | 2.11 | 4.70 |
| VRTX Vertex Pharmaceuticals Inc |
-6.44 1.23% |
517.49 | 30.22 | 24.27 | 10.36 | 6.50 | 9.99 | 24.66 |
| REGN Regeneron Pharmaceuticals Inc |
2.65 0.33% |
807.67 | 29.07 | 20.12 | 7.57 | 3.82 | 6.95 | 19.42 |
| ARGNF argenx SE |
- -% |
790.15 | 45.77 | 31.25 | 13.84 | 7.12 | 11.38 | 36.06 |
Adverum Biotechnologies, Inc., a clinical-stage company, develops gene therapy product candidates to treat ocular diseases. Its lead product candidate is ixoberogene soroparvovec (ADVM-022), a single intravitreal injection gene therapy candidate used for the treatment of patients with wet age-related macular degeneration and diabetic macular edema which is in phase 2 clinical trials. The company is developing ADVM-062 (AAV.7m8-L-opsin), a novel gene therapy product candidate for the treatment of blue cone monochromacy via a single IVT injection. Adverum Biotechnologies, Inc. has license and collaboration agreements with University of California; GenSight Biologics; Lexeo Therapeutics; and Virovek, Inc. The company was formerly known as Avalanche Biotechnologies, Inc. and changed its name to Adverum Biotechnologies, Inc. in May 2016. Adverum Biotechnologies, Inc. was incorporated in 2006 and is headquartered in Redwood City, California.
| Name | Title | Year Born |
|---|---|---|
| Dr. Laurent Fischer | Pres, CEO & Director | 1964 |
| Mr. Kishor Peter Soparkar J.D. | Chief Operating Officer | 1971 |
| Dr. Brigit Riley Ph.D. | Chief Scientific Officer | 1978 |
| Mr. John W. Rakow J.D. | Sr. VP, Gen. Counsel & Acting CFO | 1957 |
| Ms. Nancy E. Pecota | Principal Accounting Officer | 1960 |
| Mr. Heikki Jouttijarvi | Sr. VP & Head of Technical Operations | NA |
| Ms. Dena House | Sr. VP of HR, Organizational Devel. & Learning | NA |
| Ms. Carla Fiankan | Sr. VP of Regulatory Affairs | NA |
| Dr. Jim Wang Ph.D. | Chief Regulatory Officer | NA |
| Mr. Michael Steel | Sr. VP of Quality | NA |
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